Starsim “spokes”

The Starsim framework serves as a centralized “hub” for storing anything that is typically required to model the spread of diseases among agents. This includes representations of networks, diseases, populations, demographics, interventions, and products, and logic for connecting all of these things together and simulating their interactions over time.

Specific models that have been created using the Starsim framework are kept in their own separate repositories, or “spokes”. As of May 2025, Starsim’s spokes include the following models:

Spoke	Status	Description
HPVsim	Stable	Human papillomavirus (HPV) and cervical cancer
FPsim	Stable	Family planning and reproductive health
STIsim	Beta	Sexually transmitted infections, including HIV, bacterial vaginosis, chlamydia, gonorrhea, syphilis, and trichomoniasis
Rotasim	Pre-release	Rotavirus, with a focus on genetic diversity
PHCsim	Pre-release	Primary health care and health systems
MIGHTI	Pre-release	Model of Inter-Generational Health, Transmission, and Interventions (HIV and other comorbidities)
TBsim	Pre-release	Tuberculosis, including malnutrition
RVFsim	Pre-release	Rift valley fever in cattle
Typhoidsim	Pre-release	Typhoid, including environmental transmission

If you’ve developed a spoke and want it included in this list, please get in touch.

One of the strengths of Starsim is that all of these models are inter-compatible. For example, an HIV-TB coinfection model can be created by combining the HIV module from STIsim and the TB module from TBsim.

Note: the Starsim suite also includes Covasim (for modeling COVID-19). Covasim is built on the same principles as Starsim, but unlike the above tools, it is a separate codebase and is not inter-operable with the other models.